Emmanuel S Antonarakis Selected Research

abiraterone

1/2022	Clinical and genomic features of SPOP-mutant prostate cancer.
12/2021	Efficacy of systemic therapies in men with metastatic castration resistant prostate cancer harboring germline ATM versus BRCA2 mutations.
10/2021	Prospective, Single-Arm Trial Evaluating Changes in Uptake Patterns on Prostate-Specific Membrane Antigen-Targeted 18F-DCFPyL PET/CT in Patients with Castration-Resistant Prostate Cancer Starting Abiraterone or Enzalutamide.
4/2021	New approaches to targeting the androgen receptor pathway in prostate cancer.
1/2021	Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide.
1/2021	A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts.
1/2020	Prospective Multicenter Study of Circulating Tumor Cell AR-V7 and Taxane Versus Hormonal Treatment Outcomes in Metastatic Castration-Resistant Prostate Cancer.
1/2020	Neuroendocrine differentiation in usual-type prostatic adenocarcinoma: Molecular characterization and clinical significance.
1/2020	CDK12-Altered Prostate Cancer: Clinical Features and Therapeutic Outcomes to Standard Systemic Therapies, Poly (ADP-Ribose) Polymerase Inhibitors, and PD-1 Inhibitors.
1/2020	Discordant and heterogeneous clinically relevant genomic alterations in circulating tumor cells vs plasma DNA from men with metastatic castration resistant prostate cancer.

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Emmanuel S Antonarakis Research Topics

Disease

247	Prostatic Neoplasms (Prostate Cancer) 07/2022 - 11/2007
77	Neoplasms (Cancer) 07/2022 - 11/2004
35	Neoplasm Metastasis (Metastasis) 04/2022 - 09/2008
18	Circulating Neoplastic Cells 01/2021 - 01/2013
17	Disease Progression 01/2022 - 11/2010
7	Adenocarcinoma 01/2020 - 12/2012
4	Microsatellite Instability 01/2022 - 08/2017
4	Pain (Aches) 08/2021 - 10/2012
3	Fatigue 01/2022 - 01/2013
3	Diarrhea 01/2022 - 03/2011
3	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 08/2021 - 01/2019
3	Carcinoma (Carcinomatosis) 01/2020 - 04/2008
3	Carcinogenesis 01/2018 - 10/2009
2	Genomic Instability 01/2021 - 10/2017
2	Chromosomal Instability (Chromosome Stability) 01/2021 - 01/2020
2	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 12/2019
2	Hypoxia (Hypoxemia) 01/2020 - 10/2019
2	Neutropenia 10/2019 - 03/2011
2	Febrile Neutropenia 01/2019 - 03/2011
2	Hypertension (High Blood Pressure) 01/2018 - 09/2011
2	Hot Flashes 01/2018 - 01/2013
2	Melanoma (Melanoma, Malignant) 05/2012 - 01/2012

Drug/Important Bio-Agent (IBA)

67	AndrogensIBA 07/2022 - 09/2008
54	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 11/2011
46	enzalutamideIBA 01/2022 - 01/2013
41	abirateroneIBA 01/2022 - 08/2012
28	Hormones (Hormone)IBA 01/2022 - 11/2007
28	Docetaxel (Taxotere)FDA Link 12/2021 - 04/2008
21	Immune Checkpoint InhibitorsIBA 01/2021 - 05/2012
20	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2009
20	Prostate-Specific Antigen (Semenogelase)IBA 01/2022 - 10/2009
16	AntigensIBA 01/2022 - 05/2010
14	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 08/2017
13	Testosterone (Sustanon)FDA Link 07/2022 - 07/2013
13	sipuleucel-T (APC8015)FDA Link 10/2021 - 05/2010
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2010
12	VaccinesIBA 10/2021 - 02/2010
11	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2019
11	Messenger RNA (mRNA)IBA 01/2022 - 09/2014
10	Radium-223IBA 01/2021 - 10/2012
10	taxaneIBA 01/2020 - 08/2015
9	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2022 - 08/2017
8	Androgen Antagonists (Antiandrogens)IBA 01/2022 - 01/2016
8	Abiraterone AcetateIBA 12/2021 - 01/2009
8	Biological ProductsIBA 11/2021 - 05/2010
7	olaparibIBA 08/2021 - 01/2018
7	Pharmaceutical PreparationsIBA 05/2021 - 10/2009
6	pembrolizumabIBA 01/2021 - 01/2019
5	rucaparibIBA 01/2022 - 01/2020
5	Prednisone (Sone)FDA LinkGeneric 12/2021 - 05/2010
5	prostatic acid phosphataseIBA 10/2021 - 05/2010
5	IpilimumabIBA 01/2021 - 01/2012
5	LigandsIBA 01/2019 - 01/2015
4	Circulating Tumor DNAIBA 01/2022 - 02/2014
4	Cell-Free Nucleic AcidsIBA 01/2022 - 11/2015
4	apalutamideIBA 04/2021 - 12/2016
4	Taxoids (Taxanes)IBA 01/2020 - 03/2011
3	AntibodiesIBA 10/2021 - 01/2018
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020 - 02/2010
3	Androgen Receptor AntagonistsIBA 06/2019 - 12/2016
3	RNA (Ribonucleic Acid)IBA 01/2018 - 09/2016
3	cabazitaxel FDA Link 10/2017 - 01/2011
3	RadiopharmaceuticalsIBA 11/2015 - 10/2012
2	Programmed Cell Death 1 ReceptorIBA 01/2022 - 01/2018
2	antiarrhythmic peptide (AAP)IBA 12/2021 - 07/2017
2	CytokinesIBA 12/2021 - 10/2015
2	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 12/2021 - 01/2020
2	EnzymesIBA 08/2021 - 01/2009
2	darolutamideIBA 04/2021 - 01/2019
2	NivolumabIBA 01/2021 - 06/2018
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2021 - 01/2018
2	bicalutamide (Casodex)FDA LinkGeneric 11/2020 - 01/2018
2	DNA VaccinesIBA 10/2020 - 05/2010
2	B7-H1 AntigenIBA 10/2020 - 01/2018
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 02/2010
2	A-Form DNA (A-DNA)IBA 12/2019 - 05/2012
2	3- hydroxy- 17- (1H- benzimidazole- 1- yl)androsta- 5,16- dieneIBA 12/2019 - 01/2016
2	Denosumab FDA Link 01/2019 - 01/2011
2	PlatinumIBA 08/2017 - 05/2010
2	HhAntag691IBA 12/2016 - 09/2015
2	Formaldehyde (Formol)FDA Link 09/2016 - 10/2015
2	ParaffinIBA 09/2016 - 10/2015
2	Itraconazole (Sporanox)FDA LinkGeneric 04/2014 - 01/2013
2	Lenalidomide (CC 5013)FDA Link 04/2012 - 11/2010
1	Alanine Transaminase (SGPT)IBA 01/2022
1	sabizabulinIBA 01/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	ChemokinesIBA 12/2021
1	Nucleic AcidsIBA 12/2021
1	Complement System Proteins (Complement)IBA 11/2021
1	insulin receptor-related receptor (IRR)IBA 11/2021

Therapy/Procedure

149	Castration 07/2022 - 01/2009
127	Therapeutics 07/2022 - 11/2007
28	Immunotherapy 04/2022 - 02/2010
27	Drug Therapy (Chemotherapy) 11/2021 - 11/2004
20	Radiotherapy 12/2021 - 11/2007
14	Prostatectomy (Retropubic Prostatectomy) 12/2021 - 11/2007
3	Precision Medicine 08/2021 - 08/2017
2	Aftercare (After-Treatment) 01/2019 - 07/2017
1	Combination Drug Therapy (Combination Chemotherapy) 07/2022